Proteomics to uncover the hidden proteome, with exceptional analytical performance.

 

Powered by our world-leading proteomics platform, ProQuant®

Proteomics to uncover the hidden proteome, with exceptional analytical performance.

 

Powered by our world-leading proteomics platform, ProQuant®

Proteomics at RxCelerate

The proteomics team takes a non-hypothesis-driven approach to quantitatively assess proteins and protein modifications in simple or complex samples. Our patented and proprietary LC-MS/MS bottom-up proteomics methods, developed over the past 10 years, offer exceptional precision and accuracy. Together these cutting-edge technologies form ProQuant®, a flexible and solution-driven platform designed to accelerate and de-risk multiple phases of drug development.

Proteomics at RxCelerate

The proteomics team takes a non-hypothesis-driven approach to quantitatively assess proteins and protein modifications in simple or complex samples. Our patented and proprietary LC-MS/MS bottom-up proteomics methods, developed over the past 10 years, offer exceptional precision and accuracy. Together these cutting-edge technologies form ProQuant®, a flexible and solution-driven platform designed to accelerate and de-risk multiple phases of drug development.

The ProQuant® Difference

  • Unbiased analysis of proteoform diversity
  • Analyse proteins, peptides, regulated and incidental PTMs and endogenous cleavages
  • Integrated bioinformatics and expert support
  • Purpose-built platform, not retrofitted workflows
  • Standalone and integrated programmes
  • Supported through extensive in-house drug development expertise

The ProQuant® Difference

  • Unbiased analysis of proteoform diversity
  • Analyse proteins, peptides, regulated and incidental PTMs and endogenous cleavages
  • Integrated bioinformatics and expert support
  • Purpose-built platform, not retrofitted workflows
  • Standalone and integrated programmes
  • Supported through extensive in-house drug development expertise

Services

Proteomics is the large-scale study of proteins, we offer many different applications including:

Target identification

Biomarker identification

Biologics development and CMC

Label characterisation

Chemoproteomics

PTM characterisation

CUSTOM SOLUTION

We do not provide generic off-the-shelf services. We take time to truly understand your problem and deliver a tailored proteomics protocol to address it.

BEYOND ABUNDANCE

With traditional proteomics, the primary metric of quality is how many proteins are measured. ProQuant® goes further, quantifying modifications, variants, and cleavages for deeper biological insight.

ANALYTICAL PERFORMANCE

Our methods are optimised for analytical performance at the peptide and protein levels. This peptide-level resolution is necessary for rigorous assessment of proteoform-level features.

UNBIASED APPROACH

Our proprietary methods are unsupervised, and we work hard to make ProQuant® protocols as unbiased as practically possible.

Our Platform

ProQuant® is a world-leading proprietary platform technology for performing LC-MS/MS bottom-up proteomics on a wide range of biological samples, delivering exceptional precision and accuracy. The platform was designed from the ground-up to use this quantitative performance to capture a broad view of proteoform complexity, especially post-translational modifications. The platform is now being provided by RxCelerate with the power to speed up and de-risk multiple phases of the drug development pipeline.

About Us

The ProQuant® platform is offered by RxCelerate following acquisition of Methuselah Health in 2022. At RxCelerate, we take the time to understand your proteomics question first and then design an approach that has the best chance of giving you the correct answer.

Get in touch to explore how our drug development expertise, the ProQuant® platform and specialist bioinformatics can support your project.