Chemistry

Rapid compound design and synthesis to drive small molecule programmes to the clinic

Our Services

With extensive experience of taking programmes from inception through to CMC, our chemists focus on delivering the right compounds into the right assay at the right time. Combining RxCelerate’s unique in silico approaches with highly efficient compound synthesis and screening enables rapid design cycles, reaching key milestones faster than traditional methods.

Underpinning this are our robust in-house compound management and logistics capabilities that seamlessly integrate with our network of specialist partners.

COMPOUND DESIGN

Innovative compound design, combining medicinal chemistry expertise with our unique with our in silico capabilities.

SYNTHESIS MANAGEMENT

Closely managed synthesis at our trusted partner CROs guarantees quality while maintaining cost effectiveness.

COMPLEX SYNTHESIS

Extensive synthetic expertise to carry out route development for complex molecules, allowing for rapid scale-up.

cmc MANAGEMENT

Management of GMP scale up activities at preferred partner CROs, as well as coordination of pre-clinical tox campaigns.

STORAGE & LOGISTICS

Compound storage, logistics, and database management for both chemical and biological data.

PROJECT MANAGEMENT

Management of all aspects of hit finding, hit to lead and lead optimisation campaigns to ensure rapid progression.

Our Approach

With decades of experience across a wide range of therapeutic areas, our agile and dynamic medicinal chemists are highly skilled in designing active, drug-like molecules. By combining in-house expertise with trusted outsourced providers, we deliver the most efficient mix of chemistry resource for each project, ensuring rapid progress whilst keeping costs low.

Taking a bespoke approach to each programme enables us to focus on the most value-adding work, whilst close integration with our in vitro and in vivo biology teams allows us to react instantly to new data. Our focus on speed aligns our incentives with those of our clients, setting us apart from traditional CROs.

RxCelerate offers a unique business model catering to both small molecules and biologics. We work with you to drive your asset through drug discovery, preclinical research and beyond.

Our combination of integrated teams and unique technologies allows RxCelerate to develop the optimal drug discovery strategy to deliver pharma-grade drug candidates quickly and at a fraction of the cost of traditional approaches.