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RxCelerate offers bespoke animal model development services as well as a range of validated models.
RxCelerate has a growing team of skilled in vivo scientists with expertise in many different clinical disease areas. Our in vivo scientists specialise in working with clients to develop bespoke preclinical animal models that are fit for purpose and that answer the research questions you are interested in. This innovative approach allows us to tailor our models to fit your needs, which, together with our experience and knowledge, can accelerate your drug towards the clinic.
In addition to bespoke model development, we offer a wide range of validated animal models spanning many different clinical areas, including:
- Allergic asthma / eosinophilic airway disease
- AutoImmune Disease
- Cardiovascular Models
- Chronic obstructive pulmonary disease
- Injury Models
- Pain
- Pulmonary arterial hypertension
- Rheumatoid arthritis
- Osteoarthritis
- Surgical adhesions
- Stroke
- Head injury
- Heterotopic ossification
- Muscle injury
- Cancer
Our skilled team can also routinely offer:
- Pharmacokinetic profiling
- Safety and preliminary toxicology studies
- Behavioural testing
- Generation and characterisation of transgenic mice and rats
- Tissue processing
- Comprehensive histopathological scoring of diseased and healthy tissues
Thrombosis
Thrombocytes and fibrin aggregate to form blood clots, usually to prevent blood loss. Sometimes blood clots can form large enough to obstruct a blood vessel, causing a thrombosis. A clot that breaks free and travels around the body can cause an embolism